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Glossary

Adverse Drug Events (ADEs)

  • Multum defines an 'adverse drug event' as any significant or unexpected untoward reaction caused by the interaction of a medication with a patient. Reactions range from the mundane to the life threatening. Almost all of them are preventable with the proper education, knowledge, and technology.

Article References

  • Provides article references for all informational services offered—including Allergies, Pharmacology, Side Effects, Warnings, Pregnancy and Lactation Precautions, and Interactions.
  • Presented in the National Library of Medicine format with unique internal identifier.

Common Prescription Orders

  • Provides a list of the most common prescriptions for a drug product.

Dosing Monograph

  • Provides a flat text monograph of dosing information.
  • Provides adult, pediatric, and geriatric dosing.
  • Offers dosing adjustments for renal and hepatic disease, in addition to recommendations for other conditions that are pertinent to the drug.

Dose Range Checking

  • Recommends minimum/maximum dose amounts per dose or per day.
  • Provides adult, pediatric, and condition-specific dose ranges.
  • Provides additional information for specific drugs, including lifetime maximum dosing.

Drug Images and Descriptions

  • Provides a coded description of a drug's appearance.
  • Provides image files that are mapped to specific drug products.

Drug Allergy and Allergic Cross-Reactivity Checking

  • Provides allergy information checked against the active ingredients in the patient’s current drug regimen, against the active ingredients in the medications about to be ordered, and against the patient’s allergy history.
  • Generates a cross-reaction warning for allergic cross-reactivities described in the medical literature to includes the drug or drug category involved, a textual description of the reaction, and one or more references for the cross-reaction.
  • Recognizes and supports both specific drug names and drug category names.

Expanded Drug Naming Conventions

  • Provides generic and brand names for drugs including herbal products
  • Provides alternate naming conventions including short names for drugs (i.e. AZT).
  • Provides identifiers for products (i.e. allopurinol 100 mg oral tablet).
  • Provides the ability to fully customize a list of drug names.

Expert Dosing/Drug Orders/Prescriptions>

  • Provides patient-specific dosing recommendations, including both loading and maintenance doses when appropriate.
  • Recommends doses in easily dispensable units.
  • Provides recommendations based on the individual patient’s pharmacokinetics.
  • Incorporates the following considerations (when appropriate) when providing dosing recommendations: renal function, liver function, age, gender, concomitant medications, and concomitant illnesses.
  • Offers the user recommended therapies for certain disease states or conditions.
  • Provides recommendations with multiple levels of specificity: 1) drug, dose, route, and schedule information, and 2) short descriptive paragraphs detailing dosing strategy.
  • Provides options for dosing schedules when appropriate.
  • Provides textual warnings indicating when a selected drug should not be used in a particular patient.
  • Provides references on-line to the primary medical literature.

Expert Pharmacokinetics

  • Provides patient-specific pharmacokinetics based on patient characteristics.
  • Includes information on bioavailability, plasma protein binding, volume of distribution, plasma clearance, elimination half-life and excretion.

Indications – Drug Information

  • Provides a list of common indications for the drug.
  • Includes non-FDA approved indications.
  • Based on ICD-9 nomenclature.

Interactions: Drug-Drug and Drug-Food

  • Checks for drug-drug and drug-food interactions against a patient’s current medication regimen and against medications about to be ordered.
  • Analyzes both active medications and those that might still be active in the patient (based on the drug’s elimination half-life).
  • Provides a list of drugs involved when an interaction occurs, along with the level of severity of the interaction, a textual description of the interaction, suggested management of the interaction, and on-line references.
  • Provides recommended courses of action when appropriate within the textual information presented.

Interactions: Drug-Disease

  • Checks for drug-disease interactions based on patient’s current medication regimen and on medication about to be ordered against the patient’s current medical condition utilizing ICD-9 and CPT codes.
  • Analyzes both active medications and those that might still be active in the patient (based on the drug’s elimination half-life).
  • Provides plausibility for an interaction, along with the level of severity of the interaction (minor, moderate, severe), a textual description of the interaction, and on-line references.

Lactation Information

  • Identifies and describes a drug's potential hazards to nursing infants when used by lactating women.
  • Provides severity level indicator reflecting three levels of severity - relatively safe, hazardous, and no lactation information is available.
  • References all lactation information to the primary medical literature.

Lexicon Drug Information

  • Provides clinician-friendly drug names– brand name, generic name, and common abbreviations
  • Allows customers to map external drug names to Multum knowledge bases
  • Drug product information – ingredients, strength, route, formulation
  • Disease names and their associated ICD-9-CM codes
  • Coding systems – NDC, J-codes, MMDC
  • Product packaging
  • Orange book codes
  • CSA schedules
  • Drug pricing (AWP, FUL, and WAC)
  • Manufacturer information
  • Therapeutic categories

Patient Education Leaflets

  • Provides educational, drug-specific information in English or North American Spanish written on a 6th to 8th grade reading level.
  • Information adheres to 1996 FDA MedGuide recommendations.
  • Includes important side effect, drug interaction, and drug administration instructions.
  • Provides graphical icons to illustrate important hazards.
  • Take a look at some Sample Leaflets

Pharmacology

  • Provides a textual description of the pharmacologic properties of a selected drug. This information includes chemical category, mechanism of action, labeled and non-labeled indications and primary literature references.
  • Provides pharmacokinetic information containing patient-specific data.
  • Specific pharmacokinetics topics include bio-availability, plasma protein binding, volume of distribution, plasma clearance, elimination half-life, metabolism, elimination, activity of metabolites, hemodialysis clearance, and peritoneal dialysis clearance.
  • References all pharmacology information to the primary medical literature and provides keyword identifiers

Pharmacokinetics

  • Provides pharmacology and pharmacokinetic information containing patient specific data that is distinguishable from standard pharmacology and pharmacokinetic text.
  • Evaluates specific pharmacokinetic parameters for specified patients when appropriate.
  • Provides references on-line to the primary medical literature.

Pregnancy Information

  • Identifies and describes potential hazards of use during pregnancy.
  • Provides a textual description of a particular drug's potential hazards if taken by a pregnant woman, a woman who becomes pregnant during therapy, or a man who fathers a child during therapy.
  • Includes the FDA pregnancy categorization code (if available).
  • Provides, when appropriate, pregnancy alerts for drugs that are known to pose reproductive hazards when taken by female or male patients
  • Provides alerts reflecting two levels of severity - (1) relatively and/or probably safe and (2) hazardous.
  • References all pregnancy information to the primary medical literature.

Prescriptions

  • Provides a list of commonly used prescriptions based on drug and formulation.
  • Provides each order field individually in order to map to appropriate fields in clinical application.

Prescription Warning Labels

  • Provides a coded reference to a warning label that is appropriate for a prescription.
  • Warnings are supplied in both English and Spanish.
  • Can be mapped to commercially available labels or printed from a pharmacy system.

Prescription Writer - RxBuilder

  • Assists in generating correct, medically fluent orders for dug therapy based on common order elements.
  • Provides drug order information, "smart links" to drug product information, which assists in the drug ordering process.
  • Provides dynamic lists of valid values that may be specified for an order element.
  • Facilitates the creation of drug orders that translate to drug products that relate to drug products that are available off-the-shelf of the pharmacy.
  • Provides each order field individually so that it can be mapped to appropriate fields in clinical applications.

Side Effects

  • Provides side effect information in descending order of importance based on both severity and frequency of the side effect.
  • Provides side effect information in two levels; the first level consists of general side effect information organized by organ system and frequency; the second level of information, when available, incorporates greater detail including specific studies, case reports, their methodology, and the differences between study data.
  • Includes references to the primary medical literature and has key-word identifiers.

Therapeutic Categories

  • Provides a poly-hierarchical classification system for drugs.
  • Provides all therapeutic categories and sub-categories for each drug.
  • Provides all drugs for any given therapeutic category.

Therapeutic Duplication

  • Checks for duplicative medication therapy by drug and drug category against patient’s current medication regimen and medications being ordered.
  • Provides three levels of category checking, from general to very specific.

Warnings

  • Provides a description of important warnings and contraindications (not otherwise addressed by Allergy and Allergic Cross-reactivity Checking, Pregnancy and Lactation Precautions) for particular drugs.
  • No severity levels are provided. All presented warnings are considered significant.

 

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