|
| |
Aliskiren tablets
Tekturna® |
|
FDA Approval: |
March 2007 |
|
Indication: |
Hypertension |
|
Pharmacology: |
Renin inhibitor |
|
Usual Dose: |
150 mg to 300 mg orally once a day |
|
Contraindications: |
N/A |
|
Warnings: |
Pregnancy: Discontinue drug if patient becomes pregnant
Discontinue drug and treat symptoms as necessary if angioedema
occurs
Volume and salt depletion should be disontinued before starting
treatment
Treat excessive hypotension symptomatically
Caution is recommended in patients with renal impairment
Monitor renal function and electrolytes
Lactation: Discontinue the drug or discontinue breast-feeding
Safety and efficacy have not been established in pediatric
patients |
|
Pregnancy Category: |
1st trimester: C 2nd and 3rd trimester: D |
|
Side Effects: |
Angioedema, laryngeal edema, periorbital edema, edema Diarrhea,
abdominal pain, dyspepsia, gastroesophageal reflux
Cough, respiratory symptoms
Seizures, loss of consciousness |
|
Drug Interactions: |
Furosemide |
|
Every effort has been made to ensure that the
information provided by Cerner Multum, Inc. (“Multum”) is accurate, up-to-date,
and complete, but no guarantee is made to that effect. In addition, the drug
information contained herein may be time sensitive. Multum information has been
compiled for use by healthcare practitioners and end-users in the United States.
Cerner Multum does not warrant that uses outside of the United States are
appropriate.
Multum’s drug information does not endorse drugs, diagnose patients or recommend
therapy. Multum’s drug information is an informational resource designed to
assist licensed healthcare practitioners in caring for their patients and/or to
serve end-users viewing this service as a supplement to, and not a substitute
for, the expertise, skill, knowledge and judgment of healthcare practitioners.
Healthcare practitioners should use their professional judgment in using the
information provided. The absence of a warning for a given drug or drug
combination in no way should be construed to indicate that the drug or drug
combination is safe, effective or appropriate for any given patient.
Multum does not assume any responsibility for any aspect of healthcare
administered with the aid of information Multum provides.
The information contained herein is not intended to cover all possible uses,
directions, precautions, warnings, drug interactions, allergic reactions, or
adverse effects. If you have questions about the drugs you are taking, check
with your doctor, nurse or pharmacist.
Copyright 2006-2007 Cerner Multum, Inc.
|
