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Zoster Vaccine Live
ZOSTAVAX®
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FDA Approval: |
26 May 2006 |
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Indication: |
Prevention of shingles (herpes zoster) in patients
≥ 60 years |
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Pharmacology: |
Live varicella zoster vaccine |
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Usual Dose: |
0.65 mL subcutaneously one time |
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Contraindications: |
Hypersensitivity (anaphylaxis, anaphylactoid) to neomycin, gelatin
History of primary or acquired immunodeficiency
Lymphoma, bone marrow or lymphatic neoplasms
Current immunosuppressive therapy
Active untreated tuberculosis
Pregnancy |
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Warnings: |
Contact dermatitis to neomycin is not a contraindication Not
indicated for use in children
Not to be substituted for Varicella virus vaccine
Safety and efficacy not established in patients on topical,
inhaled, or low dose oral corticosteroids, or immunosuppressive
treatment
Consider deferral in acute illnesses, e.g., fever >38.5°C
(>101.3°F)
Duration of protection is not established
Not all vaccinees may be protected
Transmission of virus vaccine to susceptible individuals may
rarely occur |
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Pregnancy Category: |
C |
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Side Effects: |
Injection site reactions Headache
Respiratory infection, fever, flu syndrome, diarrhea, rhinitis,
skin disorder, respiratory disorder, asthenia
Rash |
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Drug Interactions: |
Unknown: Antiviral agents active against VZV |
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